| Game | Publisher | Date | Issue |
| Saipan | SPI | 1976 | |
| Samurai | GMT | 2007 | |
| Samurai Sunset (Command 3) | XTR | 1990 | 3 |
| Sands of Iwo Jima, The | Schutze | 2007 | |
| Santiago Campaign 1898, The (S&T 258) | Decision | 2009 | 258 |
| Saratoga | GMT | 1998 | |
| Saratoga: 1777 | Rand | 1974 | |
| Savage Station (S&T 166) | Decision | 1994 | 166 |
| Savannah | GMT | 2005 | |
| Scrimmage (S&T 37) | SPI | 1973 | 37 |
| Sea Devils (S&T 191) | Decision | 1998 | 191 |
| Sealords (S&T 243) | Decision | 2007 | 243 |
| Search & Destroy | SPI | 1975 | |
| Second Boer War, The (S&T 205) | Decision | 2000 | 205 |
| Second Front Now! (Command 44) | XTR | 1997 | 44 |
| Sedan | SPI | 1978 | |
| Sedan Campaign | Decision | 2004 | 224 |
| Sedan Campaign, 1870, The (S&T 224) | Decision | 2004 | 224 |
| Seelowe | SPI | 1974 | |
| Serbia/Galicia | SPI | 1978 | |
| Sevastopol | SPI | 1978 | |
| Seven Days Battles | Decision | 1993 | |
| Seven Seas to Victory | XTR | 1994 | |
| Seven Years War (S&T 163) | Decision | 1993 | 163 |
| Seven Years World War, The (S&T 221) | Decision | 2004 | 221 |
| Shifting Sands | MMP | 2006 | |
| Shiloh (Command 42) | XTR | 1997 | 42 |
| Shogun (Command 23) | XTR | 1993 | 23 |
| Sicily (S&T 89) | SPI | 1981 | 89 |
| Sideshow (S&T 135) | 3W | 1990 | 135 |
| Siege of Constantinople, The (S&T 66) | SPI | 1978 | 66 |
| Siege of Malta, The (Wargamer 50) | 3W | 1986 | 50 |
| Silent War | Compass | 2005 | |
| Silver Bayonet | GMT | 1990 | |
| Simple GBoH | GMT | 2000 | |
| Sinai | SPI | 1973 | |
| Singapore (S&T 96) | TSR | 1984 | 96 |
| Sixth Fleet (S&T 48) | SPI | 1975 | 48 |
| Smithereens: The End of WW2 in Europe | XTR | 1993 | |
| Sniper | SPI | 1973 | |
| Soldiers | SPI | 1971 | |
| Soldiers | West End | 1987 | |
| Soldiers (S&T 95) | TSR | 1984 | 95 |
| Solferino 1859 (Vae Victis 55) | Vae Victis | 2004 | 55 |
| Solomons Campaign | SPI | 1973 | |
| Solomons Campaign (WaW 2) | Decision | 2008 | 2 |
| Some Poles Apart: the Battle of the Westerplatte | LPS | 2007 | |
| Sorcerer | SPI | 1975 | |
| South Africa (S&T 62) | SPI | 1977 | 62 |
| Soviet Nadir, The | Perry Moore | 2002 | |
| Spanish Civil War Battles I (S&T 213) | Decision | 2002 | 213 |
| Spanish Civil War Battles II (S&T 219) | Decision | 2003 | 219 |
| Spanish Eagles | Compass Games | 2008 | |
| Spartacus | Compass Games | 2009 | |
| Spartan | SPI | 1975 | |
| SPI Baseball | SPI | 1980 | |
| SPI Introduction to Gaming | SPI | 1981 | |
| Spies! | SPI | 1981 | |
| Spitfire | SPI | 1973 | |
| SPQR 2nd Ed | GMT | 1992 | |
| SPQR Deluxe | GMT | 2008 | |
| Squad Leader | AH | 1977 | |
| SS Abyss, The | Blue Guidon | 2005 | |
| St. Vith | SPI | 1978 | |
| Stalingrad | AH | 1963 | |
| Stalingrad 1942 (Vae Victis 54) | Vae Victis | 2004 | 54 |
| Stalingrad, Battle for | SPI | 1980 | |
| Stand at Mortain | LPS | 2006 | |
| Star and Bars (Wargamer 30) | 3W | 1984 | 30 |
| Star Fleet Battles | Task Force | 1981 | |
| Star Trader (Ares 12) | SPI | 1982 | 12 |
| Starforce | SPI | 1974 | |
| Stargate | SPI | 1979 | |
| StarGate | SPI | 1979 | |
| Starsoldier | SPI | 1977 | |
| Stonewall (S&T 67) | SPI | 1978 | 67 |
| Storm of Steel | Decision | 2007 | |
| Storm Over Stalingrad | MMP | 2009 | |
| Storm Over Taierzhuang | Firefight | 2007 | |
| Storm Over Taierzhuang (ATO 25) | LPS | 2009 | 25 |
| Strange Defeat | Avalanche | 2006 | |
| Strategy I | SPI | 1971 | |
| Streets of Stalingrad | L2 | 2002 | |
| Strike Force One | SPI | 1975 | |
| Strike North (Command 39) | XTR | 1996 | 39 |
| Striking the Anvil (Battles 1) | Battles | 2009 | 1 |
| Successors | GMT | 2008 | |
| Successors (S&T 161) | Decision | 1993 | 161 |
| Suleiman the Magnificent (ATO 9) | LPS | 2004 | 9 |
| Summer Storm | Clash of Arms | 1998 | |
| Sunrise of Victory (Command 2) | XTR | 1990 | 2 |
| Supercharge | SPI | 1976 | |
| Superpowers (S&T 100) | TSR | 1985 | 100 |
| Sweden Fights On | GMT | 2003 | |
| Sword and the Stars, The | SPI | 1981 | |
| Sword of Rome | GMT | 2004 | |